
The story opens when Art is a young boy in Rego Park, New York. He's skating with some friends when his skate breaks. He falls, skins his knee and his friends skate off without him, laughing at him. He returns home to his father, Vladek, who says "Lock them in a room without food and you'll see what it is, friends" and that echoes through the story through the whole time. Vladek and his wife, Anja, are constantly being cared for then betrayed by people who were their friends or acquaintances. But the book isn't just about the Holocaust, it's also about Vladek and Anja's relationship from courtship to marriage; Vladek and Art's relationship and Art's challenge of trying to illustrate the unexplainable.
There are no twists and turns in this book. You learn from the opening that Vladek and Anja make it out alive but between the first and last pages you are engulfed in their lives and even though you know the ending, you pray to God that they make it.
And they do...at a huge cost.